124628-04-2

Basic information

• Product Name: 2-[1,4,7,10-tetraaza-7-(1-carboxy-2-benzyloxy-ethyl)-4,10-di(carboxymethyl)-cyclododecane-1-yl]-3-benzyloxypropionic acid
• CAS NO: 124628-04-2
• Molecular Weight: 644.722
• Mol File: 124628-04-2.mol

Chemical Properties

• CAS DataBase Reference: 2-[1,4,7,10-tetraaza-7-(1-carboxy-2-benzyloxy-ethyl)-4,10-di(carboxymethyl)-cyclododecane-1-yl]-3-benzyloxypropionic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[1,4,7,10-tetraaza-7-(1-carboxy-2-benzyloxy-ethyl)-4,10-di(carboxymethyl)-cyclododecane-1-yl]-3-benzyloxypropionic acid(124628-04-2)
• EPA Substance Registry System: 2-[1,4,7,10-tetraaza-7-(1-carboxy-2-benzyloxy-ethyl)-4,10-di(carboxymethyl)-cyclododecane-1-yl]-3-benzyloxypropionic acid(124628-04-2)

Safety Data

• Hazardous Substances Data: 124628-04-2(Hazardous Substances Data)

Relevant articles and documents

1,4,7,10-tetraazabicyclo[8.2.2]tetradecan-2-one, a process for the preparation thereof and the use thereof for the preparation of tetraazamacrocycles

The present invention relates to the novel compound, 1,4,7,10-tetraazabicyclo[8.2.2]tetradecan-2-one of formula (I), its preparation and the use thereof for the preparation of tetraazamacrocycles. STR1

Macrocyclic chelating agents and chelates thereof

Macrocyclic derivatives of 1,4,7,10-tetraazacyclododecane of general formula (I) hereinbelow, wherein A is a group of formula (II) hereinbelow, in which R is H or alkyl or optionally substituted benzyl or a H(OCH2 CH2)1-4-, Me(OCH2 CH2)1-4-, or Et(OCH2 CH2)1-4- group, X or O--R1, in which R1 is H or alkyl, hydroxyalkyl, alkoxyalkyl, alkoxyhydroxyalkyl or a polyoxaalkyl group or X is --NR2 R3, in which R2 and R3 are H or alkyl, hydroxyalkyl, alkoxyalkyl or alkoxyhydroxyalkyl, and B1, B2 and B3 have the same meanings as A or are H or a group of formula (III) hereinbelow, in which R4 is H or alkyl, Y is a O--R5 group, wherein R5 is H or alkyl, hydroxyalkyl, alkoxyalkyl, alkoxyhydroxyalkyl or a polyoxaalkyl group, or Y is a --NR6 R7 group, wherein R6 and R7 are H or alkyl, hydroxyalkyl, alkoxyalkyl, or alkoxyhydroxyalkyl, said derivatives optionally being salified, and the complex salts thereof, are used as pharmaceuticals and/or diagnostic agents. STR1

Macrocyclic chelating agents and chelates thereof

Macrocyclic derivatives of 1,4,7,10-tetraazacyclo-dodecane of general formula I wherein, A is a group of formula in which, R is H or alkyl or optionally substituted benzyl or a H(OCH2CH2)1 4-, Me(OCH2CH2)1 4-, or Et(OCH2CH2)1 4- group,X is O-R1, in which R1 is H or alkyl, hydroxyalkyl, alko-xyalkyl, alkoxyhydroxyalkyl or a polyoxaalkyl group or X is -NR2R3, in which R2 and R3 are H or alkyl, hydroxyalkyl, alkoxyalkyl or alkoxyhydroxyalkyl,and, B1, B2 and B3 have the same meanings as A or are H or a group of formula in which, R4 is H or alkyl, Y is a O-R5 group, wherein R5 is H or alkyl, hydroxyalkyl, alkoxyalkyl, alkoxyhydroxyalkyl or a polyoxaalkyl group, or Y is a -NR6R7 group, wherein R6 and R7 are H or alkyl, hydroxyalkyl, alkoxyalkyl or alkoxyhydroxyalkyl, said derivatives optionally being salified, and the complex salts thereof, are used as pharmaceuticals and/or diagnostic agents.