1246372-46-2

Upstream product

• 269410-22-2 4-hydroxy-3-methoxyphenylboronic acid pinacol ester 
• 230637-04-4 2-bromo-6-methylimidazo[2,1-b][1,3,4]thiadiazole 

Downstream Products

• 1246372-47-3 4-(5-iodo-6-methylimidazo[2,1-b][1,3,4]thiadiazol-2-yl)-2-methoxyphenol 

Relevant academic research and scientific papers

IMIDAZO [2, 1-B] [ 1, 3, 4 ] THIADIAZOLE DERIVATIVES

There is provided compounds of formula (I): wherein R1, R2 and R3 have meanings given in the description, and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein or lipid kinase (e.g. PI3-K, particularly class I PI3K) is desired and/or required, and particularly in the treatment of cancer.