1246403-99-5Relevant academic research and scientific papers
Synthesis of cyclic imides from nitriles and diols using hydrogen transfer as a substrate-activating strategy
Kim, Jaewoon,Hong, Soon Hyeok
supporting information, p. 4404 - 4407 (2015/01/08)
An atom-economical and versatile method for the synthesis of cyclic imides from nitriles and diols was developed. The method utilizes a Ru-catalyzed transfer-hydrogenation reaction in which the substrates, diols, and nitriles are simultaneously activated into lactones and amines in a redox-neutral manner to afford the corresponding cyclic imides with evolution of H2 gas as the sole byproduct. This operationally simple and catalytic synthetic method provides a sustainable and easily accessible route to cyclic imides.
Synthesis of cyclic imides from simple diols
Zhang, Jian,Senthilkumar, Muthaiah,Ghosh, Subhash Chandra,Hong, Soon Hyeok
supporting information; experimental part, p. 6391 - 6395 (2010/11/05)
There's something imide so strong: Cyclic imides were synthesized from simple diols with primary amines in a single step using an in-situ-generated ruthenium catalytic system. The atom-economical and operatively simple syntheses of succinimides, phthalimides, and glutarimides, which are important building blocks in natural products and drugs, was also demonstrated. Copyright
