1246404-40-9Relevant academic research and scientific papers
Development of practical methodologies for the synthesis of functionalized benzoboroxoles
Kumar, J. Sravan,Bashian, Christopher M.,Corsello, Michael A.,Jonnalagadda, Subash C.,Mereddy, Venkatram R.
, p. 4482 - 4485 (2010)
2-Formylphenylboronic acids upon reaction with activated olefins such as acrylates, methyl vinyl ketone, and acrylonitrile provide functionalized benzoboroxoles. The corresponding homologated benzoboroxoles were synthesized via the reaction of 2-formylphenylboronic acids with α- bromomethylacrylates.
Synthesis and biological evaluation of novel benzoxaboroles as potential antimicrobial and anticancer agents
Sravan Kumar,Alam,Gurrapu, Shirisha,Nelson, Grady,Williams, Michael,Corsello, Michael A.,Johnson, Joseph L.,Jonnalagadda, Subash C.,Mereddy, Venkatram R.
, p. 814 - 820 (2013/08/23)
Several novel benzoxaborole derivatives were synthesized starting from 2-formylphenylboronic acid utilizing Baylis-Hillman reaction, Barbier allylation, Passerini reaction, and aldol reaction protocols as the key step. All the synthesized benzoxaboroles have been evaluated for their antibacterial, antifungal, and anticancer activities.
