124643-33-0Relevant academic research and scientific papers
Nickel-Catalyzed Conversion of Enol Triflates into Alkenyl Halides
Hofstra, Julie L.,Poremba, Kelsey E.,Shimozono, Alex M.,Reisman, Sarah E.
supporting information, p. 14901 - 14905 (2019/11/11)
A Ni-catalyzed halogenation of enol triflates was developed and it enables the synthesis of a broad range of alkenyl iodides, bromides, and chlorides under mild reaction conditions. The reaction utilizes inexpensive, bench-stable Ni(OAc)2?4 H2O as a precatalyst and proceeds at room temperature in the presence of sub-stoichiometric Zn and either 1,5-cyclooctadiene or 4-(N,N-dimethylamino)pyridine.
