124643-47-6Relevant academic research and scientific papers
Palladium-catalysed cyclization of 2-alkynylanilines to 2-substituted indoles under an acidic two-phase system
Cacchi, Sandro,Carnicelli, Veronica,Marinelli, Fabio
, p. 289 - 296 (2007/10/02)
The cyclization of 2-alkynylanilines in the presence of PdCl2 and n-Bu4NCl under an acidic CH2Cl2-HCl two-phase system affords 2-substituted indoles in good to high yield, at room temperature.The reaction is particularly suited to the one-flask preparatio
PALLADIUM-CATALYSED COUPLING OF ARYL AND VINYL TRIFLATES OR HALIDES WITH 2-ETHYNYLANILINE: AN EFFICIENT ROUTE TO FUNCTIONALIZED 2-SUBSTITUTED INDOLES
Arcadi, A.,Cacchi, S.,Marinelli, F.
, p. 2581 - 2584 (2007/10/02)
The palladium(O)-catalysed coupling of aryl and vinyl triflates or halides with the easily available 2-ethynylaniline, followed by a palladium(II)-catalysed cyclization step, provides an efficient and very versatile procedure for the synthesis of function
