1246466-10-3

Basic information

• Product Name: tert-butyl ({5-[4-(trifluoromethyl)phenyl]furan-2-yl}methyl)carbamate
• Synonyms: tert-butyl ({5-[4-(trifluoromethyl)phenyl]furan-2-yl}methyl)carbamate
• CAS NO: 1246466-10-3
• Molecular Weight: 341.33
• Mol File: 1246466-10-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl ({5-[4-(trifluoromethyl)phenyl]furan-2-yl}methyl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl ({5-[4-(trifluoromethyl)phenyl]furan-2-yl}methyl)carbamate(1246466-10-3)
• EPA Substance Registry System: tert-butyl ({5-[4-(trifluoromethyl)phenyl]furan-2-yl}methyl)carbamate(1246466-10-3)

Safety Data

• Hazardous Substances Data: 1246466-10-3(Hazardous Substances Data)

Upstream product

• 402-43-7 p-trifluoromethylphenyl bromide 
• 178918-29-1 furan-2-ylmethylcarbamic acid tert-butyl ester 

Relevant articles and documents

Palladium-catalysed direct 5-arylation of furfurylamine or 2-(aminoalkyl)-thiophene derivatives

The palladium-catalysed direct 5-arylation of furan or thiophene derivatives bearing CH2NHR substituents (with. R = COMe or CO 2tBu) generally proceeds in good yields by using a catalysts loading of only 0.1-2 mol-%. A wide range of functions such as acetyl, propionyl, formyl, ester, nitrile, trifluoromethyl or fluoro on the aryl bromide is tolerated. Higher yields were generally obtained in the presence of electron-deficient aryl bromides than with, electron-rich aryl bromides.