1246471-11-3

Usage

Uses

Used in Organic Synthesis:
2-Bromo-5-nitro-1H-indole is used as a key intermediate in organic synthesis for the creation of various organic compounds. Its functional groups and reactivity allow for the formation of new chemical bonds and the synthesis of complex molecules, making it a versatile component in the development of novel organic materials.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 2-Bromo-5-nitro-1H-indole is utilized as a starting material for the development of pharmaceutical drugs. Its unique chemical properties and reactivity contribute to the discovery and synthesis of new drug candidates, potentially leading to the creation of innovative treatments for various medical conditions.
Used in the Synthesis of Bioactive Molecules:
2-Bromo-5-nitro-1H-indole is employed as a precursor in the synthesis of bioactive molecules, which have potential applications in medicine and biology. Its structural features enable the design and synthesis of compounds with specific biological activities, contributing to the advancement of drug discovery and development.

Upstream product

• 20870-79-5 5-nitrooxindole 

Downstream Products

• 906773-37-3 5-nitro-2-(o-tolyl)-1H-indole 
• 4993-87-7 5-nitro-2-phenyl-1H-indole 
• 31521-56-9 1-methyl-5-nitro-2-phenyl-1H-indole 

Relevant academic research and scientific papers

FUSED RING COMPOUND HAVING UREA STRUCTURE

The present invention relates to a novel fused ring compound having urea structure that exhibits excellent NAMPT activating effect, and a method using the same for treating / preventing metabolic disorder, cardiovascular and kidney disease, mitochondrial disease, neurodegenerative disease, ocular disease, and muscle wasting disorder. The present invention provides a compound represented by following formula (I) or a pharmacologically acceptable salt: Formula (I) wherein A, B, R, R2 and R3 represent the same meanings as in the claims.

SUBSTITUTED BICYCLIC COMPOUNDS AS MODULATORS OF THE ARYL HYDROCARBON RECEPTOR (AHR)

The present invention relates to bicyclic compounds which can act as aryl hydrocarbon receptor (AhR) modulators and, in particular, as AhR antagonists. The invention further relates to the use of the compounds for the treatment and/or prophylaxis of diseases and/or conditions through binding of said aryl hydrocarbon receptor by said compounds. A-B-L-C (I)

INHIBITORS OF HEPATITIS C VIRUS REPLICATION

The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

INHIBITORS OF HEPATITIS C VIRUS REPLICATION

The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.