1246472-55-8

Basic information

• Product Name: benzyl(1,2,3,4-tetrahydronaphthalen-2-yl)amine
• Synonyms: benzyl(1,2,3,4-tetrahydronaphthalen-2-yl)amine
• CAS NO: 1246472-55-8
• Molecular Weight: 237.345
• Mol File: 1246472-55-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: benzyl(1,2,3,4-tetrahydronaphthalen-2-yl)amine(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl(1,2,3,4-tetrahydronaphthalen-2-yl)amine(1246472-55-8)
• EPA Substance Registry System: benzyl(1,2,3,4-tetrahydronaphthalen-2-yl)amine(1246472-55-8)

Safety Data

• Hazardous Substances Data: 1246472-55-8(Hazardous Substances Data)

Upstream product

• 447-53-0 1,2-Dihydronaphthalene 
• 622-30-0 N-benzyl hydroxylalmine 
• 530-93-8 1,2,3,4-tetrahydronaphthalen-2-one 
• 100-46-9 benzylamine 
• 32851-50-6 benzyl(3,4-dihydronaphthalen-2-yl)amine 

Downstream Products

• 2217-42-7 (2S)-(1,2,3,4-tetrahydronaphthalen-2-yl)amine 

Relevant articles and documents

Metal- and Base-Free Room-Temperature Amination of Organoboronic Acids with N-Alkyl Hydroxylamines

We have found that readily available N-alkyl hydroxylamines are effective reagents for the amination of organoboronic acids in the presence of trichloroacetonitrile. This amination reaction proceeds rapidly at room temperature and in the absence of added metal or base, it tolerates a remarkable range of functional groups, and it can be used in the late-stage assembly of two complex units.

Indirect and direct catalytic asymmetric reductive amination of 2-tetralone

Herein we report a one-pot catalytic asymmetric reductive amination of 2-tetralone. High-throughput screening of a small library of chiral ligands allowed us to perform the enantioselective hydrogenation of the intermediate enamine with up to 60% ee and a one-pot reaction with up to 47% enantiomeric excess of the desired amine.