1246513-01-8

Basic information

• Product Name: 1,1-dimethylethyl-3-(5-phenyl-1,3,4-oxadiazol-2-yl)-1-pyrrolidinecarboxylate
• CAS NO: 1246513-01-8
• Molecular Weight: 315.372
• Mol File: 1246513-01-8.mol

Chemical Properties

• CAS DataBase Reference: 1,1-dimethylethyl-3-(5-phenyl-1,3,4-oxadiazol-2-yl)-1-pyrrolidinecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-dimethylethyl-3-(5-phenyl-1,3,4-oxadiazol-2-yl)-1-pyrrolidinecarboxylate(1246513-01-8)
• EPA Substance Registry System: 1,1-dimethylethyl-3-(5-phenyl-1,3,4-oxadiazol-2-yl)-1-pyrrolidinecarboxylate(1246513-01-8)

Safety Data

• Hazardous Substances Data: 1246513-01-8(Hazardous Substances Data)

Relevant articles and documents

Mild and convenient one-pot synthesis of 1,3,4-oxadiazoles

A mild, general, convenient, and efficient one-pot synthesis of 2-phenyl-5-substituted-1,3,4-oxadiazoles is described. Both (hetero)aryl and alkyl carboxylic acids were efficiently condensed with benzohydrazide in the presence of TBTU to give diacylhydrazine intermediates. The latter underwent a smooth TsCl-mediated cyclodehydration reaction to afford 2-phenyl-5-substituted- 1,3,4-oxadiazoles in good to very good yields.