1246610-75-2

Basic information

• Product Name: Alogliptin hydrochloride
• Synonyms: Alogliptin hydrochloride
• CAS NO: 1246610-75-2
• Molecular Weight: 375.858
• Mol File: 1246610-75-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Alogliptin hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: Alogliptin hydrochloride(1246610-75-2)
• EPA Substance Registry System: Alogliptin hydrochloride(1246610-75-2)

Safety Data

• Hazardous Substances Data: 1246610-75-2(Hazardous Substances Data)

Upstream product

• 22115-41-9 2-(bromomethyl)benzonitrile 
• 4318-56-3 3-methyl-6-chlorouracil 
• 1246610-74-1 2-[[6-[(3R)-3-tert-butoxycarbonylamino-1-piperidinyl]-3,4-dihydro-2,4-dioxo-3-methyl-1(2H)-pyrimidinyl]methyl]benzonitrile 
• 850649-61-5 alogliptin 
• 334618-23-4 3-(R)-aminopiperidine dihydrochloride 
• 865758-96-9 2-((6-chloro-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile 

Downstream Products

• 1638544-64-5 Alogliptin benzoate 

Relevant articles and documents

A preparing method for alogliptin benzoate

The invention provides a preparing method for alogliptin benzoate, and particularly provides a method for preparing 2-[[6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl]methyl]benzonitrile monobenzoate shown as a formula (I). The compound is a novel medicine treating diabetes mellitus type 2. The alogliptin benzoate (HPLC purity of which is greater than 99.95%) can be prepared in a high yield and high purity by the method, a process is simple and convenient to operate and the method is suitable for industrial production.

DIPEPTIDYL PEPTIDASE INHIBITORS

Methods of making compounds of the formula (I) wherein the variables are as defined herein. Also, methods of making compounds that may be used to inhibit dipeptidyl peptidase.