1246618-35-8Relevant academic research and scientific papers
Access to functionalized imidazolidin-2-one derivatives by Iron-catalyzed oxyamination of alkenes
Manick, Anne-Doriane,Aubert, Sidonie,Yalcouye, Boubacar,Prangé, Thierry,Berhal, Farouk,Prestat, Guillaume
, p. 11485 - 11492 (2018)
Functionalized imidazolidin-2-one were prepared by using an iron-catalyzed alkene oxyamination reaction. Hy-droxylamine derivatives were used in this atom-economical process, and the addition of an external oxidant was not required. The conditions developed were shown to be efficient for mono-, di-, and trisubstituted double bonds, and a large scope of diamino alcohol precursors were delivered in good yields with good diastereoselectivities. The mechanistic pathway was studied and appears to involve both a fused aziridine and a carbocationic species.
The stereodivergent aziridination of allylic carbamates, amides and sulfonamides
Davies, Stephen G.,Ling, Kenneth B.,Roberts, Paul M.,Russell, Angela J.,Thomson, James E.,Woods, Philip A.
experimental part, p. 6806 - 6813 (2010/09/17)
A stereodivergent protocol for the aziridination of a range of cyclic allylic amine derivatives has been developed. syn-Products can be obtained in >99:1 dr under H-bonded control and anti-products are obtained in >99:1 dr under steric control by judiciou
