1246624-38-3Relevant articles and documents
Facile synthetic method for diverse polyfunctionalized imidazoles by means of pd-catalyzed C-H bond arylation of N -methyl-4,5-dibromoimidazole
Yamauchi, Takayuki,Shibahara, Fumitoshi,Murai, Toshiaki
, p. 7185 - 7192 (2014)
C-H bond-selective arylation reaction of 4,5-dibromoimidazole with aryl iodides, catalyzed by the palladium-1,10-phenanthroline complex [Pd(phen) 2](PF6)2, has been developed. The process tolerates the presence of a variety of functional groups on the aryl halide substrates. The products formed in these reactions were transformed to a variety of polyfunctionalized imidazoles by taking advantage of selective reactions of remaining C-Br bonds.