124666-22-4 Usage
Uses
Used in Organic Synthesis:
(methylsulfinylmethyl)diphenylphosphane oxide is utilized as a ligand in metal-catalyzed reactions, playing a crucial role in facilitating and enhancing the efficiency of these processes. Its strong nucleophilic and basic characteristics contribute to its effectiveness in this application.
Used in Asymmetric Catalysis:
As a chiral ligand, (methylsulfinylmethyl)diphenylphosphane oxide is employed in asymmetric catalysis to induce selectivity in chemical reactions, leading to the preferential formation of one enantiomer over the other. This is particularly important in the pharmaceutical industry, where the desired biological activity is often associated with a specific enantiomer.
Used in Medicinal Chemistry Research:
The potential biological activity of (methylsulfinylmethyl)diphenylphosphane oxide has made it a subject of interest in medicinal chemistry. Researchers are exploring its possible applications in the development of new drugs and therapeutic agents, taking advantage of its unique chemical properties to target specific biological processes.
Check Digit Verification of cas no
The CAS Registry Mumber 124666-22-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,4,6,6 and 6 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 124666-22:
(8*1)+(7*2)+(6*4)+(5*6)+(4*6)+(3*6)+(2*2)+(1*2)=124
124 % 10 = 4
So 124666-22-4 is a valid CAS Registry Number.
124666-22-4Relevant academic research and scientific papers
Exploiting Substrate Diversity for Preparing Synthetically Valuable Sulfoxides via Asymmetric Hydrogenative Kinetic Resolution
Fernández-Pérez, Héctor,Grabulosa, Arnald,Lao, Joan R.,Vidal-Ferran, Anton
supporting information, (2020/07/24)
A detailed study is disclosed on the Rh-mediated hydrogenative kinetic resolution of α,β-unsaturated sulfoxides with alkyl and aryl substituents at the α-, E- and Z-positions of the double bond. This stereoselective catalytic methodology has enabled the p
Stereoselective synthesis of (E)-Vinyl Sulfoxides by the Horner-Wittig reaction
Van Steenis, Jan Hein,Van Es, Joseph Johannes Gerardus Steven,Van Der Gen, Arne
, p. 2787 - 2793 (2007/10/03)
The Horner-Wittig reaction of sulfinylmethyl-substituted di-phenylphosphane oxides 1-3 with aldehydes is reported. In a straightforward synthesis, (E)-vinyl sulfoxides 4 (R1 = Ph), 5 (R1 = Me) and 6 (R1=pTol) were formed m
A Convenient Procedure for the Oxidation of Sterically Hindered Sulfides to Sulfoxides
Drabowicz, Jozef,Lyzwa, Piotr,Popielarczyk, Miroslaw,Mikolajczyk, Marian
, p. 937 - 938 (2007/10/02)
A selective and efficient method for the oxidation of sterically hindered sulfides to sulfoxides is described, which involves the use of hydrogen peroxide in methanol in the presence of catalytic amounts of a mixture of sulfuric acid and isoamyl, isopropy
