1246661-37-9Relevant academic research and scientific papers
A new and practical grignard-coupling-fluorination sequence: Synthesis of 2-aryl fluoroarenes
Anbarasan, Pazhamalai,Neumann, Helfried,Beller, Matthias
, p. 1775 - 1778 (2010)
A new strategy for the synthesis of 2-aryl-and 2-heteroaryl fluoroarenes has been developed. An intermolecular domino Grignard-coupling-fluorination sequence affords a range of 2-fluorobiaryls from aryl bromides under mild conditions. This methodology can be further extended to the synthesis of 2′-aryl-2-fluorobiphenyls.
