1246748-27-5Relevant academic research and scientific papers
Highly effective and enantioselective α-amination of aldehydes promoted by chiral proline amide-thiourea bifunctional catalysts
Fu, Ji-Ya,Huang, Qing-Chun,Wang, Qiao-Wei,Wang, Li-Xin,Xu, Xiao-Ying
supporting information; experimental part, p. 4870 - 4873 (2010/10/02)
A series of secondary amine-thiourea catalysts derived from l-proline and chiral diamine were prepared and first applied to highly enantioselective amination of unmodified aldehydes with various azodicarboxylates in excellent yields (up to 99%) and enanti
Effective construction of quaternary stereocenters by highly enantioselective α-amination of branched aldehydes
Fu, Ji-Ya,Xu, Xiao-Ying,Li, Yan-Chun,Huang, Qing-Chun,Wang, Li-Xin
supporting information; experimental part, p. 4524 - 4526 (2010/11/21)
A highly efficient enantioselective α-amination of branched aldehydes with azadicarboxylates promoted by chiral proline-derived amide thiourea bifunctional catalysts was developed for the first time, affording the adducts bearing quaternary stereogenic centers with excellent yields (up to 99%) and enantioselectivities (up to 97% ee).
Effective asymmetric Michael addition of acetone to nitroalkenes promoted by chiral proline amide-thiourea bifunctional catalysts
Wang, Qiao-Wei,Peng, Lin,Fu, Ji-Ya,Huang, Qing-Chun,Wang, Li-Xin,Xua, Xiaoying
experimental part, p. 340 - 351 (2010/08/04)
A series of secondary amine-thiourea catalysts 1a-1d derived from L-proline and chiral diamine were prepared and successfully applied to the Michael addition of acetone to trans-nitroalkenes in excellent yields (up to 99%) and enantioselectivities (44-91%
