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  • 1246748-48-0 Structure
  • Basic information

    1. Product Name: C21H24N2O3S
    2. Synonyms:
    3. CAS NO:1246748-48-0
    4. Molecular Formula:
    5. Molecular Weight: 384.499
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1246748-48-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: C21H24N2O3S(CAS DataBase Reference)
    10. NIST Chemistry Reference: C21H24N2O3S(1246748-48-0)
    11. EPA Substance Registry System: C21H24N2O3S(1246748-48-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1246748-48-0(Hazardous Substances Data)

1246748-48-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1246748-48-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,4,6,7,4 and 8 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1246748-48:
(9*1)+(8*2)+(7*4)+(6*6)+(5*7)+(4*4)+(3*8)+(2*4)+(1*8)=180
180 % 10 = 0
So 1246748-48-0 is a valid CAS Registry Number.

1246748-48-0Downstream Products

1246748-48-0Relevant articles and documents

Synthesis and biochemical evaluation of a range of (4-substituted phenyl)sulfonate derivatives of 4-hydroxybenzyl imidazole-based compounds as potent inhibitors of 17α-hydroxylase/17,20-lyase (P450 17α) derived from rat testicular microsomes

Owen, Caroline P.,Shahid, Imran,Lee, Wai-Yee,Ahmed, Sabbir

, p. 5345 - 5348 (2010)

We report the synthesis, biochemical evaluation and rationalisation of the inhibitory activity of a range of (4-substituted phenyl)sulfonate derivatives of 4-hydroxybenzyl imidazole against the two components of 17α-hydroxylase/ 17,20-lyase (P45017α), namely, 17α-hydroxylase (17α-OHase) and 17,20-lyase (lyase). The results show the compounds to be highly potent inhibitors with limited selectivity towards the lyase component [e.g., toluene-4-sulfonic acid 4-imidazol-1-ylmethyl-phenyl ester (4) possessed an IC50 value of 40 nM against 17α-OHase and 30 nM against lyase].

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