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CAS

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1246749-62-1

tert-butyl 6-[2-chloro-5-fluorophenyl]-2,6-diazaspiro[3.3]heptane-2-carboxylate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1246749-62-1 Structure

  • Basic information

    1. Product Name: tert-butyl 6-[2-chloro-5-fluorophenyl]-2,6-diazaspiro[3.3]heptane-2-carboxylate
    2. Synonyms: tert-butyl 6-[2-chloro-5-fluorophenyl]-2,6-diazaspiro[3.3]heptane-2-carboxylate
    3. CAS NO:1246749-62-1
    4. Molecular Formula:
    5. Molecular Weight: 326.798
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1246749-62-1.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: tert-butyl 6-[2-chloro-5-fluorophenyl]-2,6-diazaspiro[3.3]heptane-2-carboxylate(CAS DataBase Reference)
    10. NIST Chemistry Reference: tert-butyl 6-[2-chloro-5-fluorophenyl]-2,6-diazaspiro[3.3]heptane-2-carboxylate(1246749-62-1)
    11. EPA Substance Registry System: tert-butyl 6-[2-chloro-5-fluorophenyl]-2,6-diazaspiro[3.3]heptane-2-carboxylate(1246749-62-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1246749-62-1(Hazardous Substances Data)

1246749-62-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1246749-62-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,4,6,7,4 and 9 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1246749-62:
(9*1)+(8*2)+(7*4)+(6*6)+(5*7)+(4*4)+(3*9)+(2*6)+(1*2)=181
181 % 10 = 1
So 1246749-62-1 is a valid CAS Registry Number.

1246749-62-1Downstream Products

1246749-62-1Relevant articles and documents

Discovery of potent and liver-targeted stearoyl-CoA desaturase (SCD) inhibitors in a bispyrrolidine series

Lachance, Nicolas,Gareau, Yves,Guiral, Sebastien,Huang, Zheng,Isabel, Elise,Leclerc, Jean-Philippe,Leger, Serge,Martins, Evelyn,Nadeau, Christian,Oballa, Renata M.,Ouellet, Stephane G.,Powell, David A.,Ramtohul, Yeeman K.,Tranmer, Geoffrey K.,Trinh, Thao,Wang, Hao,Zhang, Lei

scheme or table, p. 980 - 984 (2012/03/26)

Inhibition of stearoyl-CoA desaturase (SCD) activity represents a potential novel mechanism for the treatment of metabolic disorders including obesity and type II diabetes. To circumvent skin and eye adverse events observed in rodents with systemically-distributed SCD inhibitors, our research efforts have been focused on the search for new and structurally diverse liver-targeted SCD inhibitors. This work has led to the discovery of novel, potent and structurally diverse liver-targeted bispyrrolidine SCD inhibitors. These compounds possess suitable cellular activity and pharmacokinetic properties to inhibit liver SCD activity in a mouse pharmacodynamic model.

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