1246764-86-2Relevant articles and documents
Prenylflavonoids and prenyl/alkyl-phloroacetophenones: Synthesis and antitumour biological evaluation
Basabe,De Román,Marcos,Diez,Blanco,Bodero,Mollinedo,Sierra,Urones
experimental part, p. 4258 - 4269 (2010/10/01)
Several prenylflavonoids have been synthesised and tested against human tumour cell lines. The prenyl unit has been geranyl or a labdane diterpene. These labdane-flavonoids have been synthesised for the first time. The antitumour activity increase with the prenylation at C-8 position. Twenty-three C and O-prenylated acylphloroglucinols have been synthesised as well. In this case the C-alkylation products have resulted, in general, more active.
