1246780-01-7Relevant academic research and scientific papers
Synthesis and biological activity of some cinnolinothiazoles
Jadhav, Yogesh P.,Dawane, Kushal H.,Athlekar,Patil,Bobade,Chowdhary
, p. 419 - 420 (2012/01/13)
Several 2-substituted anilino-4-(6-chloro-1H-cinnoline-4-one) thiazoles HBr (3a-I) were synthezied. 3-Acetyl-6-chloro-1H-cinnoline-4-one 1 was brominated using phenyltrimethylammonium tribromide (PTT) as selective a-brominating agent to obtain corresponding bromoacetyl product 2 which when condensed with various substituted phenyl thioureas yielded corresponding title compounds (3a-I). They were screened for antibacterial and antifungal activity.
