N-Desmethyl Trifluoperazine-d8 Dihydrochloride is a labeled metabolite derived from the antipsychotic drugs Trifluoperazine (TFP) and Fluphenazine. It is a white powder in its chemical form, which is commonly used in various applications across different industries.
1246814-84-5
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Basic information
- Product Name: N-Desmethyl Trifluoperazine-d8 Dihydrochloride
- Synonyms: Demethyl- trifluoperazine;Demethyl-trifluoperazine-d8 Dihydroc;N-Desmethyl Trifluoperazine-d8 Dihydrochloride;Deshydroxyethyl Fluphenazine-d8 Dihydrochloride;10-[3-(1-Piperazinyl-d8)propyl]-2-(trifluoroMethyl)-;10-[3-(1-Piperazinyl-d8)propyl]-2-(trifluoromethyl)phenothiazine Dihydrochloride;10-[3-(1-Piperazinyl-d8)propyl]-2-(trifluoromethyl)-10H-phenothiazine Dihydrochloride
- CAS NO:1246814-84-5
- Molecular Formula: C20H22F3N3S
- Molecular Weight: 393.4689896
- EINECS: N/A
- Product Categories: Intermediates & Fine Chemicals;Isotope Labeled Compounds;Metabolites & Impurities;Pharmaceuticals;Sulfur & Selenium Compounds;Isotope Labelled Compounds
- Mol File: 1246814-84-5.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: Methanol, Water
- CAS DataBase Reference: N-Desmethyl Trifluoperazine-d8 Dihydrochloride(CAS DataBase Reference)
- NIST Chemistry Reference: N-Desmethyl Trifluoperazine-d8 Dihydrochloride(1246814-84-5)
- EPA Substance Registry System: N-Desmethyl Trifluoperazine-d8 Dihydrochloride(1246814-84-5)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1246814-84-5(Hazardous Substances Data)
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1246814-84-5 Usage
Uses
Used in Pharmaceutical Industry:N-Desmethyl Trifluoperazine-d8 Dihydrochloride is used as a labeled metabolite for the development and analysis of antipsychotic drugs, specifically Trifluoperazine (TFP) and Fluphenazine. Its application in this industry is crucial for understanding the metabolic pathways and pharmacokinetics of these drugs, which can help in optimizing their efficacy and safety.
Used in Research and Development:
In the field of research and development, N-Desmethyl Trifluoperazine-d8 Dihydrochloride serves as a valuable tool for studying the mechanisms of action, pharmacological effects, and potential side effects of the antipsychotic drugs it is derived from. This information can be used to develop new drugs with improved therapeutic profiles or to modify existing drugs to minimize adverse effects.
Used in Quality Control and Standardization:
N-Desmethyl Trifluoperazine-d8 Dihydrochloride is also used in the quality control and standardization of pharmaceutical products containing Trifluoperazine (TFP) and Fluphenazine. It helps in ensuring the accuracy and consistency of drug content, potency, and purity, which is essential for maintaining the safety and efficacy of these medications.
Used in Analytical Chemistry:
In analytical chemistry, N-Desmethyl Trifluoperazine-d8 Dihydrochloride is employed as a reference compound for the development and validation of analytical methods, such as high-performance liquid chromatography (HPLC), mass spectrometry (MS), and other chromatographic techniques. These methods are used to detect, quantify, and identify the presence of the parent drugs and their metabolites in biological samples, such as blood, plasma, or urine.
Used in Drug Metabolism Studies:
N-Desmethyl Trifluoperazine-d8 Dihydrochloride is utilized in drug metabolism studies to investigate the metabolic pathways and enzyme interactions of Trifluoperazine (TFP) and Fluphenazine. This information is vital for understanding the pharmacokinetics, drug-drug interactions, and potential toxicity of these antipsychotic medications.
Check Digit Verification of cas no
The CAS Registry Mumber 1246814-84-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,4,6,8,1 and 4 respectively; the second part has 2 digits, 8 and 4 respectively.Calculate Digit Verification of CAS Registry Number 1246814-84:
(9*1)+(8*2)+(7*4)+(6*6)+(5*8)+(4*1)+(3*4)+(2*8)+(1*4)=165
165 % 10 = 5
So 1246814-84-5 is a valid CAS Registry Number.
1246814-84-5Upstream product
1246814-84-5Downstream Products
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N-Desmethyl Trifluoperazine-d8 Dihydrochloride
