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Nitisinone-13C6, also known as a herbicidal triketone, is a compound that inhibits 4-hydroxyphenylpyruvate dioxygenase (HPPD), an enzyme that plays a crucial role in plastoquinone biosynthesis in plants and tyrosine catabolism in mammals. It is characterized by its tan solid appearance and is primarily recognized for its application in the treatment of inherited tyrosinemia type I, a rare genetic disorder.

1246815-63-3

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1246815-63-3 Usage

Uses

Used in Pharmaceutical Industry:
Nitisinone-13C6 is used as a therapeutic agent for the treatment of inherited tyrosinemia type I. It functions by inhibiting the enzyme HPPD, which is involved in the metabolic pathway of tyrosine. This inhibition helps to reduce the accumulation of toxic metabolites that can cause severe liver and kidney damage in patients with the disease.
Used in Agricultural Industry:
Nitisinone-13C6 is also utilized as a herbicidal agent, specifically as a triketone that targets the HPPD enzyme in plants. By inhibiting this enzyme, the compound disrupts the biosynthesis of plastoquinone, which is essential for photosynthesis and plant growth. This action makes Nitisinone-13C6 an effective tool for controlling unwanted plant growth in agricultural settings.

Check Digit Verification of cas no

The CAS Registry Mumber 1246815-63-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,4,6,8,1 and 5 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1246815-63:
(9*1)+(8*2)+(7*4)+(6*6)+(5*8)+(4*1)+(3*5)+(2*6)+(1*3)=163
163 % 10 = 3
So 1246815-63-3 is a valid CAS Registry Number.

1246815-63-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[2-nitro-4-(trifluoromethyl)benzoyl]cyclohexane-1,3-dione

1.2 Other means of identification

Product number -
Other names Nitisone-13C6

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1246815-63-3 SDS

1246815-63-3Upstream product

1246815-63-3Downstream Products

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