1246815-83-7

Usage

Uses

Used in Pharmaceutical Industry:
2-N-Propyl Pramipexole is used as a pharmaceutical compound for its potential therapeutic applications. As a derivative of Pramipexole, it may exhibit similar pharmacological properties, making it a candidate for the treatment of various medical conditions. Its specific application and efficacy would depend on further research and development in the pharmaceutical field.
Used in Research and Development:
2-N-Propyl Pramipexole is used as a research compound for studying its chemical properties, potential interactions with other molecules, and possible applications in various industries. Its off-white to pale beige solid form makes it suitable for laboratory experiments and analysis.

Relevant academic research and scientific papers

Synthetic method of pramipexole impurity B

The invention belongs to the technical field of medicine production and in particular to a preparation method of a pramipexole impurity. The synthetic method of the pramipexole impurity B comprises the following steps of: S1, adding (S)-2,6-diamino-4,5,6,7-tetrahydrobenzothiazole, alkali, propionic anhydride and DMAP into an organic solvent to synthesize (S)-N,N'-(4,5,6,7-tetrahydrobenzothiazole-2,6-diyl)dipropanamide; and S2, adding the (S)-N,N'-(4,5,6,7-tetrahydrobenzothiazole-2,6-diyl)dipropanamide obtained by the reaction in the S1 into an organic solvent and reducing system, wherein the reaction product is the pramipexole impurity B. The synthetic method of the pramipexole impurity B is simple in process route and convenient to operate, and the synthesized pramipexole impurity B can be used as a reference substance for detecting related substances of pramipexole, and the method is applied to quality control of pramipexole and related preparations.

B prumipexole hydrochloride method for synthesis of the material

The invention provides a synthetic method of a pramipexole dihydrochloride related substance B shown by a formula I. The pramipexole dihydrochloride related substance B synthesized by the synthetic method is high in purity and can be directly used for quality control of related substances in pramipexole dihydrochloride; moreover, the synthetic method provided by the invention is simple and convenient in operation, readily-available in raw material, mild in reaction condition, good in repeatability, and suitable for production of the related substance B.