1246819-49-7 Usage
Uses
Used in Pharmaceutical Industry:
ε-Aminocaproic Acid-d10 Hydrochloride is used as an intermediate in the synthesis of esters of 6-aminohexanoic acid, which serve as antibacterial agents. The incorporation of deuterium atoms in the molecule can provide insights into the structure-activity relationship and improve the drug's stability and efficacy.
Used in Enzyme Inhibition Research:
ε-Aminocaproic Acid-d10 Hydrochloride is utilized as a research tool to study the inhibition of various enzymes, such as chymotrypsin, Factor VIIa, lysine carboxypeptidase, plasmin, and plasminogen activator. The deuterium-labeled compound can help in understanding the enzyme-inhibitor interactions and the underlying mechanisms of action.
Used in Analytical Chemistry:
ε-Aminocaproic Acid-d10 Hydrochloride can be employed as an internal standard or a stable isotope-labeled compound in analytical techniques, such as mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy. The presence of deuterium atoms allows for accurate quantification and identification of the compound in complex samples.
Used in Biochemical and Biomedical Research:
ε-Aminocaproic Acid-d10 Hydrochloride can be used in biochemical and biomedical research to investigate the role of ε-aminocaproic acid in various biological processes and its potential therapeutic applications. The deuterium-labeled compound can provide valuable information on the compound's metabolism, distribution, and excretion in biological systems.
Check Digit Verification of cas no
The CAS Registry Mumber 1246819-49-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,4,6,8,1 and 9 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1246819-49:
(9*1)+(8*2)+(7*4)+(6*6)+(5*8)+(4*1)+(3*9)+(2*4)+(1*9)=177
177 % 10 = 7
So 1246819-49-7 is a valid CAS Registry Number.
1246819-49-7Relevant academic research and scientific papers
Anastasiadis, Aphrodite,Separovic, Frances,White, Jonathan
, p. 747 - 750 (2001)
Gramicidin A (gA) analogues with a biotin attached to the C-terminus by an aminocaproyl linker are used as ion channels in the AMBRI biosensor and are referred to as biotinylated gA. In order to examine the conformation and dynamics of the aminocaproyl linker by 2H solid-state nuclear magnetic resonance, the synthesis of deuterated aminocaproic acid is required. We report on the synthesis of (D10)-6-aminocaproic acid from commercially available perdeuterated cyclohexanol and its covalent attachment to the C-terminal group of gA to form gAXDXB.
