1246820-41-6

Basic information

• Product Name: Fluindione-d4
• Synonyms: Fluindione-d4;2-(4-Fluorophenyl)-1H-indene-1,3(2H)-dione-d4;2-(p-Fluorophenyl)-1,3-indandione-d4;LM 123-d4;Previscan-d4;2-(2,3,5,6-tetradeuterio-4-fluorophenyl)indene-1,3-dione
• CAS NO: 1246820-41-6
• Molecular Formula: C15H9FO2
• Molecular Weight: 240.2291632
• Product Categories: Intermediates & Fine Chemicals;Isotope Labelled Compounds;Pharmaceuticals;Stable Isotopes
• Mol File: 1246820-41-6.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Fluindione-d4(CAS DataBase Reference)
• NIST Chemistry Reference: Fluindione-d4(1246820-41-6)
• EPA Substance Registry System: Fluindione-d4(1246820-41-6)

Safety Data

• Hazardous Substances Data: 1246820-41-6(Hazardous Substances Data)

Usage

Description

Fluindione-d4 is a synthetic derivative of the vitamin K antagonist, fluindione, which is commonly used as an anticoagulant in the medical field. It is characterized by its ability to inhibit the activity of vitamin K epoxide reductase, a key enzyme in the synthesis of blood clotting factors. The addition of deuterium (D4) to the fluindione molecule may enhance its stability, solubility, or other properties, making it a valuable compound for research and therapeutic applications.

Uses

Used in Pharmaceutical Industry:
Fluindione-d4 is used as a vitamin K antagonist for its anticoagulant properties. It serves as a valuable tool in the treatment and prevention of blood clots, particularly in patients with conditions such as deep vein thrombosis, pulmonary embolism, and atrial fibrillation. By inhibiting the activity of vitamin K epoxide reductase, Fluindione-d4 reduces the synthesis of clotting factors, thereby decreasing the risk of clot formation.
Additionally, Fluindione-d4 may be utilized in research settings to study the mechanisms of blood clotting and the role of vitamin K in this process. Its deuterated form may provide insights into the structural and functional aspects of the enzyme-inhibitor interactions, potentially leading to the development of more effective and targeted anticoagulant therapies.