1246832-74-5Relevant academic research and scientific papers
Formal syntheses of dihydrocorynantheine and isorhynchophylline via proline catalyzed Mannich-Michael reaction
Nagata, Kazuhiro,Ishikawa, Hitomi,Tanaka, Ayako,Miyazaki, Michiko,Kanemitsu, Takuya,Itoh, Takashi
, p. 1791 - 1798 (2010)
Proline catalyzed Mannich-Michael reaction of 3-ethyl-3-buten-2-one with 9-tosyl-3,4-dihydro-β-carboline proceeded in a highly stereoselective manner. The reaction was applied to formal syntheses of dihydrocorynantheine and isorhynchophylline. The Japan I
Enantioselective formal aza-Diels-Alder reactions of enones with cyclic imines catalyzed by primary aminothioureas
Lalonde, Mathieu P.,McGowan, Meredeth A.,Rajapaksa, Naomi S.,Jacobsen, Eric N.
supporting information, p. 1891 - 1894 (2013/04/10)
A highly enantio- and diastereoselective synthesis of indolo- and benzoquinolizidine compounds has been developed through the formal aza-Diels-Alder reaction of enones with cyclic imines. This transformation is catalyzed by a new bifunctional primary aminothiourea that achieves simultaneous activation of both the enone and imine reaction components.
