124688-06-8

Basic information

• Product Name: 2,3-DIHYDRO-2,2-DIMETHYL-5-METHOXY-1H-INDEN-1-ONE
• Synonyms: 2,3-DIHYDRO-2,2-DIMETHYL-5-METHOXY-1H-INDEN-1-ONE
• CAS NO: 124688-06-8
• Molecular Formula: C₁₂H₁₄O₂
• Molecular Weight: 190.24
• Mol File: 124688-06-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,3-DIHYDRO-2,2-DIMETHYL-5-METHOXY-1H-INDEN-1-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-DIHYDRO-2,2-DIMETHYL-5-METHOXY-1H-INDEN-1-ONE(124688-06-8)
• EPA Substance Registry System: 2,3-DIHYDRO-2,2-DIMETHYL-5-METHOXY-1H-INDEN-1-ONE(124688-06-8)

Safety Data

• Hazardous Substances Data: 124688-06-8(Hazardous Substances Data)

Upstream product

• 165072-42-4 5-methoxy-2,2-dimethyl-2,3-dihydro-1H-indene-1-ol 

Downstream Products

• 165072-42-4 5-methoxy-2,2-dimethyl-2,3-dihydro-1H-indene-1-ol 
• 1259381-69-5 C₂₈H₂₄O₂ 
• 1259381-70-8 C₂₈H₂₄O₂ 
• 1259381-71-9 C₂₉H₂₆O₃ 

Relevant articles and documents

The role of oxygen acidity on the side-chain fragmentation of ring methoxylated benzocycloalkenol radical cations

The reactivity of 2,2-dimethyl-5-methoxyindan-1-ol (1) and 2,2-dimethyl-6-methoxytetral-1-ol (2) radical cations has been studied both in acidic and basic solution. At pH≤4 both 1.+ and 2.+ undergo Cα-H deprotonation as the exclusive reaction with k=4.6×104 and 3.2×104 s-1, respectively. In basic solution 1.+ and 2.+ behave as oxygen acids undergoing -OH-induced α-OH deprotonation in a diffusion controlled process (k-OH≈1010 M-1 s-1). An intermediate alkoxyl radical is formed which undergoes a 1,2-hydrogen atom shift in competition with C-C β-scission (with 1.+) or as the exclusive pathway (with 2.+). A behavior which is interpreted in terms of the greater ease of ring-opening of a five membered ring as compared to a six-membered one.