1246923-35-2Relevant academic research and scientific papers
Constructing multiply substituted arenes using sequential palladium(II)-catalyzed C-H olefination
Engle, Keary M.,Wang, Dong-Hui,Yu, Jin-Quan
supporting information; experimental part, p. 6169 - 6173 (2010/11/18)
A balancing act: Complementary catalytic systems are described, in which the reactivity/selectivity balance in PdII-catalyzed ortho-C=H olefination can be modulated to enable sequential C=H functionalization for the rapid preparation of 1,2,3- trisubstituted arenes 1. Additionally, a rare example of iterative C=H activation, in which a newly installed functional group directs subsequent C=H activation has been demonstrated (2).
