1246923-86-3Relevant academic research and scientific papers
Enantiomerically pure and highly substituted alicyclic α,α- difluoro ketones: Potential inhibitors for malarial aspartic proteases, the plasmepsins
Faeh, Christoph,Mathys, Roland,Hardegger, Leo A.,Meyer, Solange,Bur, Daniel,Diederich, Francois
supporting information; experimental part, p. 4617 - 4629 (2010/10/21)
The design and synthesis of novel fluorinated building blocks is of major interest in the development of new pharmaceuticals and agrochemicals. A quantitative search in the Protein Data Bank (PDB) manifests the use of di- and trifluoro hydrates for bindin
