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tert-butyl 4-(5-{[(5-chloro-3-methyl-1-benzothien-2-yl)sulfonyl][4-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)butyl]amino}-2-methoxyphenyl)piperazine-1-carboxylate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1246948-55-9

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1246948-55-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1246948-55-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,4,6,9,4 and 8 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1246948-55:
(9*1)+(8*2)+(7*4)+(6*6)+(5*9)+(4*4)+(3*8)+(2*5)+(1*5)=189
189 % 10 = 9
So 1246948-55-9 is a valid CAS Registry Number.

1246948-55-9Relevant academic research and scientific papers

Development of molecular probes for the human 5-HT6 receptor

Vázquez-Villa, Henar,González-Vera, Juan A.,Benhamú, Bellinda,Viso, Alma,Fernández De La Pradilla, Roberto,Junquera, Elena,Aicart, Emilio,López-Rodríguez, María L.,Ortega-Gutiérrez, Silvia

supporting information; experimental part, p. 7095 - 7106 (2010/12/25)

In this work we report the synthesis of a set of labeled ligands targeting the human 5-HT6 receptor (h5-HT6R). Among the synthesized compounds, fluorescent probe 10 (Ki = 175 nM and -f = 0.21) and biotinylated derivative 15 (Ki = 90 nM) deserve special attention because they enable direct observation of the h5-HT6R in cells. Thus, they represent the first molecular probes for 5-HT6R visualization. These results are the starting point for introducing a variety of tags in these or other 5-HT6R ligand scaffolds aimed at the development of optimized probes with tailored profiles in terms of fluorescence, affinity, or selectivity.

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