1246956-27-3

Upstream product

• 1275518-47-2 C₂₆H₂₄F₃NO₅ 

Downstream Products

• 1246956-30-8 dibenzyl 2-((2R,3R)-1,1,1-trifluoro-3-formyl-4-phenylbutan-2-yl)malonate 
• 1246956-34-2 dibenzyl 2-((2R,3R)-1,1,1-trifluoro-3-formylhexan-2-yl)malonate 
• 1246956-36-4 dibenzyl 2-((2R,3R)-1,1,1-trifluoro-3-formylhex-5-en-2-yl)malonate 
• 1246956-31-9 dibenzyl 2-((2R,3R)-1,1,1-trifluoro-3-formylbutan-2-yl)malonate 
• 1246956-33-1 dibenzyl 2-((2R,3R)-1,1,1-trifluoro-3-formylpentan-2-yl)malonate 
• 1246956-35-3 dibenzyl 2-((2R,3R)-1,1,1-trifluoro-3-formyl-4-methylpentan-2-yl)malonate 
• 1275518-18-7 dibenzyl (R)-2-(2,2,2-trifluoro-1-(5-nitro-1H-indol-3-yl)ethyl)malonate 
• 1275517-93-5 dibenzyl (R)-2-(2,2,2-trifluoro-1-(5-methoxy-1H-indol-3-yl)ethyl)malonate 
• 1275518-23-4 dibenzyl (R)-2-(2,2,2-trifluoro-1-(1H-pyrrol-3-yl)ethyl)malonate 
• 1275518-11-0 dibenzyl (R)-2-(1-(6-bromo-1H-indol-3-yl)-2,2,2-trifluoroethyl)malonate 
• 1275518-03-0 dibenzyl (R)-2-(2,2,2-trifluoro-1-(7-methyl-1H-indol-3-yl)ethyl)malonate 
• 1275517-84-4 dibenzyl (R)-2-(2,2,2-trifluoro-1-(1H-indol-3-yl)ethyl)malonate 

Relevant academic research and scientific papers

Enantioselective friedel-crafts alkylation of indoles with trifluoroethylidene malonates by copper-bis(oxazoline) complexes: Construction of trifluoromethyl-substituted stereogenic tertiary carbon center

An enantioselective alkylation of indoles with trifluoroethylidene malonates catalyzed by copper(II)-bis (oxazoline) complexes has been developed. The expected adducts with a stereogenic tertiary carbon center bearing a trifluoromethyl group were obtained

Enantioselective organocatalytic Michael addition of aldehydes to trifluoroethylidene malonates

An efficient, highly enantioselective, organocatalytic Michael addition reaction of aldehydes with trifluoroethylidene malonates is described. The asymmetric reaction provided highly optically pure β-trifluoromethyl aldehydes which can be conveniently tra