1246959-90-9

Upstream product

• 53293-00-8 hex-5-ynoic acid 
• 35087-23-1 N,N-dimethylhex-5-ynoylamide 
• 585-76-2 m-bromobenzoic acid 
• 863713-72-8 3-(6-(dimethylamino)-6-oxohex-1-yn-1-yl)benzoic acid 
• 17814-85-6 (4-carboxybutyl)triphenylphosphonium bromide 
• 91856-55-2 Ν,Ν-dimethylamino 4-(carboxybutyl)triphenylphosphonium bromide 
• 52178-50-4 Methyl 3-formylbenzoate 

Downstream Products

• 1246960-11-1 3-[(1Z)-6-(dimethylamino)-6-oxohex-1-en-1-yl]-N-(2-triisopropylsilyloxy-1-methyl-ethyl)benzamide 

Relevant academic research and scientific papers

COMPOUNDS FOR TREATING DISORDERS ASSOCIATED WITH BK CHANNEL MODULATION

The present invention relates to a compound of formula I, or a pharmaceutically acceptable salt, solvate or prodrug thereof, wherein: Z is OR16 or NR17R18; R16 is H or alkyl; R17 is H or alkyl; R

BENZAMIDE DERIVATIVES USEFUL IN THE TREATMENT OF MUSCULAR DISORDERSAND PAIN AND FOR CONTROLLING SPASTICITY AND TREMORS

The present invention relates to a compound of formula I, or a pharmaceutically acceptable salt thereof : (I) wherein: n is 0 or 1; R1 is selected from H, alkyl and aralkyl, wherein said alkyl and aralkyl groups may be optionally substituted by one or mor

PROCESS FOR PREPARING CARBOXYLIC ACID AMIDES USEFUL IN THE TREATMENT OF MUSCULAR DISORDERS

The present invention relates to a process for preparing a compound of formula wherein: R2 is cycloalkyl or alkyl, each of which may be optionally substituted; Y is -CONR3R4, -CN or CO2R5; R3, R4 and R5 are each independently H or alkyl; n is 1 to 6; wherein said process comprising the steps of : (i) treating a compound of formula (IV), where R1 is alkyl, with a compound of formula (V) and forming a compound of formula (IIIb); (ii) treating said compound of formula (IIIb) with a compound of formula (Il) to form a compound of formula (I).