1246961-09-0

Basic information

• Product Name: 3-(((2-Phenylthiazol-5-yl)methyl)amino)isoquinolin-1(2H)-one
• Synonyms: 3-(((2-Phenylthiazol-5-yl)methyl)amino)isoquinolin-1(2H)-one
• CAS NO: 1246961-09-0
• Molecular Weight: 333.414
• Mol File: 1246961-09-0.mol

Chemical Properties

• CAS DataBase Reference: 3-(((2-Phenylthiazol-5-yl)methyl)amino)isoquinolin-1(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(((2-Phenylthiazol-5-yl)methyl)amino)isoquinolin-1(2H)-one(1246961-09-0)
• EPA Substance Registry System: 3-(((2-Phenylthiazol-5-yl)methyl)amino)isoquinolin-1(2H)-one(1246961-09-0)

Safety Data

• Hazardous Substances Data: 1246961-09-0(Hazardous Substances Data)

Upstream product

• 298705-56-3 (2-phenyl-1,3-thiazol-5-yl-methyl)amine 
• 6627-91-4 2-cyanomethylbenzoic acid 

Relevant articles and documents

3-(Hetarylamino)- and 3-[(hetarylmethyl)amino]-isoquinolin-1(2H)-ones

The reaction of 2-(cyanomethyl)benzoic acid with amines RNH2 (R = Ar, Het, CH2Ar, CH2Het) leads to the formation of the corresponding 3-NHR-isoquinolin-1(2H)-ones. When R = CH2Ar and CH2Het, there is a side reaction involving hydrolysis of the hydrolytically-unstable intermediates, derivatives of 2-(2-amino-2-iminoethyl) benzoic acid, leading to 2-R-isoquinoline-1,3(2H,4H)-diones.