1246997-94-3Relevant academic research and scientific papers
An expedient synthesis of indolo[1,2-a]quinolines via Mn(OAc)3-mediated oxidative free radical cyclization and NaI/O2-assisted dealkoxycarbonylation/ aerobic oxidation cascade
Lee, Hyun Seung,Kim, Se Hee,Kim, Yu Mi,Kim, Jae Nyoung
experimental part, p. 5071 - 5075 (2011/01/04)
An expedient synthetic procedure of indolo[1,2-a]quinolines was developed using a sequential Cu-mediated N-arylation of indole, Mn(OAc) 3-mediated oxidative free radical cyclization, and NaI/O 2-assisted concomitant dealkoxycarbonylation/aerobic oxidation. The last step was replaced by a palladium-catalyzed decarboxylation/elimination protocol for the allyl ester derivatives.
