1247017-95-3Relevant academic research and scientific papers
Palladium-catalyzed intramolecular C-H arylation of 2-halo-: N -Boc- N -arylbenzamides for the synthesis of N-H phenanthridinones
Hu, Quan-Fang,Gao, Tian-Tao,Shi, Yao-Jie,Lei, Qian,Yu, Luo-Ting
, p. 13879 - 13890 (2018/04/25)
A palladium catalyzed synthesis of N-H phenanthridinones was developed via C-H arylation. The protocol gives phenanthridinones regioselectively by one-pot reaction without deprotection. It exhibits broad substrate scope and affords targets in up to 95% yields. Importantly, it could be applied for the less reactive o-chlorobenzamides.
Synthesis of axially chiral amino acid and amino alcohols via additive-ligand-free Pd-catalyzed domino coupling reaction and subsequent transformations of the product amidoaza[5]helicene
Furuta, Takumi,Yamamoto, Junya,Kitamura, Yuki,Hashimoto, Ayano,Masu, Hyuma,Azumaya, Isao,Kan, Toshiyuki,Kawabata, Takeo
supporting information; experimental part, p. 7010 - 7013 (2010/11/24)
Novel optically active axially chiral amino acid and amino alcohols have been synthesized efficiently via lactam ring-opening, with the aid of an optically active alcohol, amidoaza[5]helicene 5, which has been readily prepared by an additive-ligand-free P
