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124702-80-3

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124702-80-3 Usage

Description

5,6-Dihydroxy-indan-1-one, a bicyclic chemical compound with the molecular formula C9H8O3, features an indan-1-one moiety with hydroxy groups at the 5 and 6 positions. Its phenolic nature endows it with potential antioxidant and free radical scavenging capabilities. 56-dihydroxy-indan-1has garnered attention in the fields of chemistry and biochemistry due to its unique structure and properties, and it has been studied for its potential applications in pharmaceuticals and as a building block in organic synthesis.

Uses

Used in Pharmaceutical Industry:
5,6-Dihydroxy-indan-1-one is used as a pharmaceutical candidate for its potential antioxidant properties, which can help in the development of treatments targeting oxidative stress-related conditions. Its free radical scavenging ability also makes it a promising agent for the prevention and treatment of various diseases associated with oxidative damage.
Used in Organic Synthesis:
In the field of organic synthesis, 5,6-dihydroxy-indan-1-one serves as a valuable building block. Its unique structure allows for the synthesis of various complex organic compounds, contributing to the development of new pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Antioxidant Formulations:
5,6-Dihydroxy-indan-1-one is used as an antioxidant in various formulations, such as food additives, cosmetics, and industrial applications, to prevent oxidation and extend the shelf life of products. Its ability to scavenge free radicals helps protect against oxidative damage and degradation.
Used in Research and Development:
Due to its unique structure and properties, 5,6-dihydroxy-indan-1-one is utilized in research and development for the exploration of new chemical reactions, synthesis pathways, and potential applications in various industries. Its study contributes to the advancement of knowledge in chemistry and biochemistry, paving the way for future innovations.

Check Digit Verification of cas no

The CAS Registry Mumber 124702-80-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,4,7,0 and 2 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 124702-80:
(8*1)+(7*2)+(6*4)+(5*7)+(4*0)+(3*2)+(2*8)+(1*0)=103
103 % 10 = 3
So 124702-80-3 is a valid CAS Registry Number.

124702-80-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 5,6-Dihydroxy-2,3-dihydro-1H-inden-1-one

1.2 Other means of identification

Product number -
Other names 5,6-dihydroxy-2,3-dihydroinden-1-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:124702-80-3 SDS

124702-80-3Relevant articles and documents

Cyanopyridyl containing 1,4-dihydroindeno[1,2-c]pyrazoles as potent checkpoint kinase 1 inhibitors: Improving oral biovailability

Tong, Yunsong,Przytulinska, Magdalena,Tao, Zhi-Fu,Bouska, Jennifer,Stewart, Kent D.,Park, Chang,Li, Gaoquan,Claiborne, Akiyo,Kovar, Peter,Chen, Zehan,Merta, Philip J.,Bui, Mai-Ha,Olson, Amanda,Osterling, Donald,Zhang, Haiying,Sham, Hing L.,Rosenberg, Saul H.,Sowin, Thomas J.,Lin, Nan-horng

, p. 5665 - 5670 (2007)

A series of 1,4-dihydroindeno[1,2-c]pyrazole compounds with a cyanopyridine moiety at the 3-position of the tricyclic pyrazole core was explored as potent CHK-1 inhibitors. The impact of substitutions at the 6 and/or 7-position of the core on pharmacokinetic properties was studied in detail. Compounds carrying a side chain with an ether linker at the 7-position and a terminal morpholino group, such as 29 and 30, exhibited much-improved oral biovailability in mice as compared to earlier generation inhibitors. These compounds also possessed desirable cellular activity in potentiating doxorubicin and will serve as valuable tool compounds for in vivo evaluation of CHK-1 inhibitors to sensitize DNA-damaging agents.

Efficient demethylation of aromatic methyl ethers with HCl in water

Bomon, Jeroen,Bal, Mathias,Achar, Tapas Kumar,Sergeyev, Sergey,Wu, Xian,Wambacq, Ben,Lemière, Filip,Sels, Bert F.,Maes, Bert U. W.

supporting information, p. 1995 - 2009 (2021/03/26)

A green, efficient and cheap demethylation reaction of aromatic methyl ethers with mineral acid (HCl or H2SO4) as a catalyst in high temperature pressurized water provided the corresponding aromatic alcohols (phenols, catechols, pyrogallols) in high yield. 4-Propylguaiacol was chosen as a model, given the various applications of the 4-propylcatechol reaction product. This demethylation reaction could be easily scaled and biorenewable 4-propylguaiacol from wood and clove oil could also be applied as a feedstock. Greenness of the developed methodversusstate-of-the-art demethylation reactions was assessed by performing a quantitative and qualitative Green Metrics analysis. Versatility of the method was shown on a variety of aromatic methyl ethers containing (biorenewable) substrates, yielding up to 99% of the corresponding aromatic alcohols, in most cases just requiring simple extraction as work-up.

Indanone derivative 5,6-dyhydroxy-2,3-dihydrocaroone-1H-indene-1-ketone and preparation method thereof

-

Paragraph 0038-0047, (2016/11/28)

The invention provides indanone derivative 5,6-dyhydroxy-2,3-dihydrocaroone-1H-indene-1-ketone and a preparation method thereof, relates to indanone derivatives and a preparation method thereof and aims to solve the technical problems that in the prior art, the operation process is complex, controllability is poor, the product yield is low, and stability is poor. The structural formula of the indanone derivative can be found in the specification. The preparation method includes the steps that 1, a 5,6-dimethoxy-2,3-dihydrocaroone-1H-indene-1-ketone solution is prepared; 2, boron tribromide is added for a reaction; 3, a saturated sodium bicarbonate solution is added for neutralizing the boron tribromide; 4, extraction and spin steaming are conducted. A product obtained through the method has good stability and a high yield; by means of the method, two methoxyl functional groups adjacent to indanone are converted into hydroxyl, and the activity of the indanone is greatly improved so that indanone derivatives provided with different substituent groups can be synthesized on the indanone, and crystal complexes of different spacial structures are configured. The preparation method is used for preparing the 5,6-dyhydroxy-2,3-dihydrocaroone-1H-indene-1-ketone.

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