1247067-01-1

Basic information

• Product Name: C₆₃H₁₀₇N₅O₂₆S
• Synonyms: C₆₃H₁₀₇N₅O₂₆S
• CAS NO: 1247067-01-1
• Molecular Weight: 1382.63
• Mol File: 1247067-01-1.mol

Chemical Properties

• CAS DataBase Reference: C₆₃H₁₀₇N₅O₂₆S(CAS DataBase Reference)
• NIST Chemistry Reference: C₆₃H₁₀₇N₅O₂₆S(1247067-01-1)
• EPA Substance Registry System: C₆₃H₁₀₇N₅O₂₆S(1247067-01-1)

Safety Data

• Hazardous Substances Data: 1247067-01-1(Hazardous Substances Data)

Upstream product

• 794524-05-3 C₄₈H₈₅N₅O₂₄ 
• 6553-96-4 2,4,6-triisopropylphenylsulfonyl chloride 

Downstream Products

• 1437593-56-0 C₆₄H₁₁₇N₅O₂₃S 
• 1437593-37-7 C₃₉H₇₇N₅O₁₃S 

Relevant articles and documents

Di-alkylated paromomycin derivatives: Targeting the membranes of Gram positive pathogens that cause skin infections

A collection of paromomycin-based di-alkylated cationic amphiphiles differing in the lengths of their aliphatic chain residues were designed, synthesized, and evaluated against 14 Gram positive pathogens that are known to cause skin infections. Paromomyci

MEMBRANE-TARGETING AMINOGLYCOSIDE-BASED CATIONIC AMPHIPHILES AND THERAPEUTIC USES

The present invention relates to amphiphilic aminoglycoside (AG) derivatives, especially derivatives of tobramycin, kanamycin A and paromomycin comprising hydrophobic side chains linked to the AG moiety by various linkers. These novel derivatives are useful as broad spectrum antibacterial agents targeting bacterial cell membranes, while having minimal toxicity due to non-selective targeting of eukaryotic cell membranes. The present invention further relates to methods for preparing the novel derivatives, pharmaceutical compositions including such compounds, and methods of using these compounds and compositions, especially as membrane-targeting antibacterial agents for treating bacterial infections, and for inhibiting bio film growth.