124716-41-2Relevant academic research and scientific papers
Synthesis of optically active β-lactams by the photolytic reaction of imines with optically active chromium carbene complexes
Hegedus,Imwinkelried,Alarid-Sargent,Dvorak,Satoh
, p. 1109 - 1117 (2007/10/02)
Optically active chromium carbene complexes utilizing (S)-valine- and (R)-phenylglycine-derived chiral auxillaries were synthesized and subjected to photolytic reaction with a number of imines. Optically active β-lactams were produced in good to excellent chemical yield and with high diastereoisomeric excess. Procedures for removal of the chiral auxillary to produce the optically active free amino β-lactams were developed.
