124716-76-3Relevant academic research and scientific papers
Synthesis and Reactions of 3-Hydroxy-2-nosyloxy Esters Produced by the Stereoselective Reduction of 2-Nosyloxy-3-keto Esters
Hoffman, Robert V.,Kim, Hwa-Ok
, p. 6759 - 6764 (2007/10/02)
The reduction of 2-nosyloxy-3-keto esters is an effective method for the preparation of 3-hydroxy-2-nosyloxy esters.The reduction is stereoselective for the syn isomer.The anti isomer can be produced as the major product by the addition of p-nitrobenzenesulfonyl peroxide to ketene bis-silyl acetal derivatives of 3-hydroxy esters.The diastereomers are separable chromatographically and can be converted stereospecifically to glycidic esters and 2-azido-3-hydroxy esters.As such they appear to have excellent potential as versatile synthetic intermediates for the synthesis of 1,2,3-trifunctional substances.
Synthesis of 2-oxy> 3-Keto Esters from 3-Keto Esters and (p-Nitrophenyl)sulfonyl Peroxide
Hoffman, Robert V.,Wilson, Anna Lee,Kim, Hwa-Ok
, p. 1267 - 1270 (2007/10/02)
The preparation of 2-oxy> β-keto esters from β-keto esters and (p-nitrophenyl)sulfonyl peroxide is described.High yields are obtained for a variety of structural types.One β-diketone was also used and gave comparable success.Thes
