124717-64-2Relevant academic research and scientific papers
Plant antitumor agents. Synthesis and biological activity of ring D and ring E modified analogues of camptothecin
Nicholas,Wani,Manikumar,Wall,Kohn,Pommier
, p. 972 - 978 (2007/10/02)
The total synthesis of the pentacyclic camptothecin analogues 3 and 4 in 11 steps from p-tolualdehyde is described. The overall shape of compound 3 is the same as that of potent, naturally occurring camptothecin (1a). Despite the near spatial identity of
