12475-99-8

Basic information

• Product Name: Losartan potassium
• Synonyms: Llosartan;Losartan(Cozaar)
• CAS NO: 12475-99-8
• Molecular Formula: C22H22ClKN6O
• Molecular Weight: 0
• Product Categories: Active Pharmaceutical Ingredients
• Mol File: 12475-99-8.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Losartan potassium(CAS DataBase Reference)
• NIST Chemistry Reference: Losartan potassium(12475-99-8)
• EPA Substance Registry System: Losartan potassium(12475-99-8)

Safety Data

• Hazardous Substances Data: 12475-99-8(Hazardous Substances Data)

Usage

General Description

Losartan potassium is a medication used to treat high blood pressure and reduce the risk of stroke in certain patients. It belongs to a class of drugs known as angiotensren II receptor blockers, or ARBs, which work by blocking the action of a substance in the body that causes blood vessels to narrow, thus lowering blood pressure and improving blood flow. Losartan potassium is typically taken orally in the form of a tablet, and is often prescribed in combination with other medications to further control blood pressure. It is generally well-tolerated, but some potential side effects may include dizziness, lightheadedness, and hyperkalemia. It is important to follow the dosage instructions provided by a healthcare provider when taking losartan potassium.

Related news

A statistical study on the development of micro particulate sustained drug delivery system for Losartan potassium (cas 12475-99-8) by 32 factorial design approach08/17/2019

The purpose of this study was to investigate the effect of polymer and surfactant concentration on drug loading and in vitro drug release of micro particulate drug delivery system of Losartan potassium (LST). Microparticles were prepared by O/O solvent emulsification method. A 32 full factorial ...detailed

A clean photometric method for the determination of Losartan potassium (cas 12475-99-8) in pharmaceuticals exploiting light scattering effect and employing a multicommuted flow analysis approach08/16/2019

This paper describes an environmentally friendly procedure for the determination of losartan potassium (Los-K) in pharmaceuticals. The photometric method was based on the light scattering effect due to particles suspension, which were formed by the reaction of Los-K with Cu (II) ions. The method...detailed

Significance of Metabolites in Bioequivalence: Losartan potassium (cas 12475-99-8) as a Case Study08/14/2019

ABSTRACTEstimation of metabolite data as a supportive evidence of comparable therapeutic outcome is recommended by various guidance documents. However, a consensus on using it solely to establish bioequivalence (BE) is lacking as parent drug is believed to detect pharmacokinetic differences betw...detailed

Utilizing Guar Gum for Development of “Tabs In Cap’ System of Losartan potassium (cas 12475-99-8) for Chronotherapeutics08/13/2019

The project was aimed to achieve biphasic pulsed drug release of losartan potassium by fabricating ‘Tabs in cap’ system wherein drug loaded tablets sandwiched the erodible guar gum time spacer tablet. The system was capsulated in non biodegradable body capped with water soluble cap. The system...detailed

Design and evaluation of controlled release Losartan potassium (cas 12475-99-8) microcapsules08/12/2019

BackgroundThe main objective of the present investigation is to design controlled release microcapsules of losartan potassium using Eudragit S100 as a release rate retarding polymer.detailed

Modulating effect of Losartan potassium (cas 12475-99-8) on the mutagenicity and recombinogenicity of doxorubicin in somatic cells of Drosophila melanogaster08/10/2019

Losartan potassium is an antihypertensive drug in the angiotensin II receptor antagonist (ARA) class. Some studies claim that, in addition to regulating blood pressure, this class of drug has anticancer properties. The objective of this study was to evaluate the genotoxic and antigenotoxic poten...detailed