124755-01-7Relevant academic research and scientific papers
A novel synthesis of 1,3-benzodiazepin-2-ones using intramolecular heck reaction
Hayashi, Masahito,Sai, Hiroshi,Horikawa, Hiroshi
, p. 1331 - 1335 (2007/10/03)
The formation of the skeleton of 1,3-benzodiazepin-2-one could be efficiently achieved by intramolecular Heck reaction. This methodology was well applicable to the preparation of optically pure 4-substituted 1,3-benzodiazepin-2-ones starting from easily available α-amino acids.
Syntheses and reactions of silyl carbamates. 2. A new mode of cyclic carbamate formation from tert-butyldimethylsilyl carbamate
Sakaitani, Masahiro,Ohfune, Yasufumi
, p. 1150 - 1158 (2007/10/02)
Stereoselective construction of 1,2 and 1,3 amino hydroxyl systems was achieved by the intramolecular trapping of the N-tert-butyldimethylsilyloxycarbonyl species (silyl carbamate) activated by fluoride ion. The reaction of the silyl carbamate with 1,2-sy
Synthesis and Absolute Structure of Galantinamic Acid
Hori, Keiko,Ohfune, Yasufumi
, p. 3886 - 3888 (2007/10/02)
The structure of galantinamic acid (2) has been confirmed to be (2R,3S,5S,6R)-25 by the stereoselective synthesis of each of the eight diastereomers derived from L-lysine; total synthesis of the natural form was accomplished by starting from D-lysine
