1247748-11-3Relevant academic research and scientific papers
Cu(II)-catalyzed acylation by thiol esters under neutral conditions: Tandem acylation-wittig reaction leading to a one-pot synthesis of butenolides
Matsuo, Kazumasa,Shindo, Mitsuru
supporting information; experimental part, p. 5346 - 5349 (2011/01/05)
The first catalytic acylation of alcohols with a thiol ester present in Wittig reagents under neutral conditions catalyzed by the Cu(II) salt through a push-pull mechanism is reported. Furthermore, a new methodology for the one-pot lactonization of acyloins by a copper catalyst is developed. The synthetic utility of this method for the synthesis of natural products is shown.
Direct carbon-carbon bond formation via reductive soft enolization: A kinetically controlled syn-aldol addition of α-halo thioesters and enolizable aldehydes
Sauer, Scott J.,Garnsey, Michelle R.,Coltart, Don M.
supporting information; experimental part, p. 13997 - 13999 (2010/12/24)
The direct addition of enolizable aldehydes and α-halo thioesters to produce β-hydroxy thioesters enabled by reductive soft enolization is reported. The transformation is operationally simple and efficient and has the unusual feature of giving high syn-se
