1247898-91-4Relevant academic research and scientific papers
Synthesis of [1,2,4]oxadiazolo[4,5-a]thiazolo[2,3-b]pyrimidin- 9(10H)-ones via 1,3-dipolar cycloaddition of nitrile oxide to thiazolo[3,2-a]pyrimidin-3-one derivatives
Li, Xiaofang,Zheng, Aiting,Liu, Bin,Yu, Xianyong,Yi, Pinggui
experimental part, p. 977 - 980 (2010/11/24)
A new class of [1,2,4]oxadiazolo[4,5-a]thiazolo[2,3-b]pyrimidin-9(10H)-one was prepared in moderate yields by the reaction of nitrile oxide with 2-arylmethylidene-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-3-one. The reaction site of dipolarphile is the C=N of thiazolo[3,2-a]pyrimidin-3-one rather than the expected C=C of aryl-methylidene. The structures of the products were characterized thoroughly by IR, elemental analysis, MS, and NMR analysis.
