124807-89-2

Basic information

• Product Name: CHEMBRDG-BB 5226017
• Synonyms: CHEMBRDG-BB 5226017;7-BROMO-1,5-DIMETHYL-1H-INDOLE-2,3-DIONE;IFLAB-BB F0919-3040;7-bromo-1,5-dimethyl-1H-indole-2,3-dione(SALTDATA: FREE);7-bromo-1,5-dimethylindoline-2,3-dione
• CAS NO: 124807-89-2
• Molecular Formula: C₁₀H₈BrNO₂
• Molecular Weight: 254.08
• Mol File: 124807-89-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: CHEMBRDG-BB 5226017(CAS DataBase Reference)
• NIST Chemistry Reference: CHEMBRDG-BB 5226017(124807-89-2)
• EPA Substance Registry System: CHEMBRDG-BB 5226017(124807-89-2)

Safety Data

• Hazardous Substances Data: 124807-89-2(Hazardous Substances Data)

Upstream product

• 108938-16-5 7-bromo-5-methyl-2,3-dihydro-1H-indole-2,3-dione 
• 74-88-4 methyl iodide 
• 1383675-20-4 N-(2-bromo-4-methylphenyl)-N-methylpropiolamide 
• 124807-88-1 2-bromo-4-methyl-α-isonitrosoacetanilide 
• 583-68-6 2-bromo-p-toluidine 
• 77-78-1 dimethyl sulfate 

Relevant articles and documents

Oxidative Radical Cyclization of N-methyl-N-arylpropiolamide to Isatins via Cleavage of the Carbon-carbon Triple Bond

A radical cyclization of N-methyl-N-arylpropiolamide to isatins via an oxidative cleavage of a carbon-carbon triple bond has been developed. In the presence of oxone and NaNO2, a variety of N-methyl-N-arylpropiolamides were smoothly transformed into isatins. A nitration reaction proceeded along with the oxidative cyclization; both nitrated and non-nitrated isatins were obtained in a one-pot reaction with moderate to good total yields. This is the first example for the synthesis of isatins via the oxidative radical cleavage of a carbon-carbon triple bond. (Figure presented.).

Synthesis of some Newer Biologically Active Substituted-3-((6-substituted-2-hydrazono)benzothiazolyl)-2-indolines. Part LIV

5-Bromo- and 5-methyl-7-bromoisatins (1a) have been synthesised and transformed into the corresponding 1-methyl analogs (1b). 1a and 1b have been condensed with 2-hydrazinobenzothiazoles to yield 3 and 4.Mannich condensation of 3 using morpholine and piperidine furnished the corresponding 1-morpholino/piperidinomethyl analogs (5).The compounds have been characterised by means of ir and pmr spectroscopy.