1248260-49-2

Usage

Uses

Used in Pharmaceutical Synthesis:
1-(3-iodophenyl)-2-pyrrolidinone is used as an intermediate in the pharmaceutical industry for the synthesis of various drugs, particularly antipsychotic and antihypertensive medications. Its unique structure and properties make it a valuable component in the development of these therapeutic agents.
Used in Organic Compound Preparation:
1-(3-iodophenyl)-2-pyrrolidinone is also utilized in the preparation of organic compounds, highlighting its versatility and importance in the field of organic chemistry.
Used as a Reagent in Chemical Reactions:
1-(3-iodophenyl)-2-pyrrolidinone serves as a reagent in a range of chemical reactions, further demonstrating its utility and applicability in chemical processes.
Used in Medicinal Chemistry and Drug Discovery:
Due to its pharmacological properties and structural features, 1-(3-iodophenyl)-2-pyrrolidinone may have potential applications in medicinal chemistry and drug discovery, contributing to the advancement of novel therapeutic agents and treatments.

Upstream product

• 1426918-48-0 4-bromo-N-(3-iodo-phenyl)-butyramide 
• 626-01-7 3-Iodoaniline 

Downstream Products

• 1426918-49-1 4-[6-(4-hydroxy-phenyl)-3-{(E)-2-[3-(2-oxo-pyrrolidin-1-yl)-phenyl]-vinyl}-1-(tetrahydropyran-2-yl)-1H-pyrazolo[3,4-b]pyridine-4-carbonyl]-piperazine-1-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

6-(4-Hydroxy-phenyl)-3-styryl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors

The present invention relates to pyrazolo[3,4-b]pyridine compounds of the formula, in which R1, R2, R3, R4 and R5 are defined as indicated below. The compounds of the formula are kinase C (PKC) inhibitors, and are useful for the treatment of diseases associated with diabetes and diabetic complications, such as, diabetic nephropathy, diabetic neuropathy and diabetic retinopathy, for example. The invention furthermore relates to the use of compounds of the formula, in particular as active ingredients in pharmaceuticals, and pharmaceutical compositions comprising them.

6-(4-HYDROXY-PHENYL)-3-STYRYL-1H-PYRAZOLO[3,4-b]PYRIDINE-4-CARBOXYLIC ACID AMIDE DERIVATIVES AS KINASE INHIBITORS

The present invention relates to pyrazolo[3,4-b]pyridine compounds of the formula I, in which R1, R2, R3, R4 and R5 are defined as indicated below. The compounds of the formula I are kinase inhibitors, and are useful for the treatment of diseases associated with diabetes and diabetic complications, such as, diabetic nephropathy, diabetic neuropathy and diabetic retinopathy, for example. The invention furthermore relates to the use of compounds of the formula I, in particular as active ingredients in pharmaceuticals, and pharmaceutical compositions comprising them.

6-(4-HYDROXY-PHENYL)-3-STYRYL-1H-PYRAZOLO[3,4-B]PYRIDINE-4-CARBOXYLIC ACID AMIDE DERIVATIVES AS KINASE INHIBITORS

The present invention relates to pyrazolo[3,4-b]pyridine compounds of the formula I, in which R1, R2, R3, R4 and R5 are defined as indicated below. The compounds of the formula I are kinase inhibitors, and are useful for the treatment of diseases associated with diabetes and diabetic complications, such as, diabetic nephropathy, diabetic neuropathy and diabetic retinopathy, for example. The invention furthermore relates to the use of compounds of the formula I, in particular as active ingredients in pharmaceuticals, and pharmaceutical compositions comprising them.