124830-99-5

Basic information

• Product Name: P(3)-1-(2-nitro)phenylethylguanosine 5'-O-triphosphate
• Synonyms: P(3)-1-(2-nitro)phenylethylguanosine 5'-O-triphosphate;Guanosine 5'-(Tetrahydrogen Triphosphate) P''-[1-(2-Nitrophenyl)ethyl]ester;Guanosine 5'-Triphosphate P3-[1-(2-Nitrophenyl)ethyl]ester
• CAS NO: 124830-99-5
• Molecular Formula: C18H23N6O16P3
• Molecular Weight: 672.327103
• Product Categories: Aromatics;Bases & Related Reagents;Carbohydrates & Derivatives;Nucleotides;Phosphorylating and Phosphitylating Agents;Aromatics, Carbohydrates & Derivatives, Nucleotides, Bases & Related Reagents, Phosphorylating and Phosphitylating Agents
• Mol File: 124830-99-5.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: P(3)-1-(2-nitro)phenylethylguanosine 5'-O-triphosphate(CAS DataBase Reference)
• NIST Chemistry Reference: P(3)-1-(2-nitro)phenylethylguanosine 5'-O-triphosphate(124830-99-5)
• EPA Substance Registry System: P(3)-1-(2-nitro)phenylethylguanosine 5'-O-triphosphate(124830-99-5)

Safety Data

• Hazardous Substances Data: 124830-99-5(Hazardous Substances Data)

Usage

Description

P(3)-1-(2-nitro)phenylethylguanosine 5'-O-triphosphate, also known as caged phosphate, is a modified nucleotide that has been chemically modified to be inactive until it is released by a specific stimulus, such as light. It is a derivative of guanosine 5'-triphosphate (GTP) with a nitrophenylethyl group attached to the 1-position of the purine base, and a triphosphate group at the 5' position of the ribose sugar. This modification allows for the controlled release of GTP in biological systems, making it a valuable tool for studying the role of GTP in various cellular processes.

Uses

Used in Biochemistry Research:
P(3)-1-(2-nitro)phenylethylguanosine 5'-O-triphosphate is used as a caged compound for the controlled release of GTP in biochemical experiments. This allows researchers to study the effects of GTP on cellular processes in a controlled manner, without the compound being active until it is specifically released.
Used in Cell Biology Research:
P(3)-1-(2-nitro)phenylethylguanosine 5'-O-triphosphate is used as a caged compound for the controlled release of GTP in cell biology experiments. This enables researchers to investigate the role of GTP in cellular signaling pathways and other processes within living cells.
Used in Photolysis Studies:
P(3)-1-(2-nitro)phenylethylguanosine 5'-O-triphosphate is used as a caged phosphate in Fourier transform IR photolysis studies. This allows researchers to investigate the structural changes and dynamics of the compound upon photolysis, providing insights into the mechanism of GTP release and its role in cellular processes.
Used in Drug Delivery Systems:
P(3)-1-(2-nitro)phenylethylguanosine 5'-O-triphosphate can be used as a caged compound in drug delivery systems, allowing for the targeted release of GTP in specific cells or tissues. This could potentially be used to develop targeted therapies for various diseases, including cancer, by controlling the release of GTP in tumor cells or other diseased tissues.