1248348-67-5 Usage
General Description
N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(1S,2S)-2-(1-pyrrolidinyl)cyclohexyl]-Thiourea is a chemical compound that is used in research and experimental studies. It is a thiourea derivative, and it is often used as a reagent in chemical reactions and synthesis processes. N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(1S,2S)-2-(1-pyrrolidinyl)cyclohexyl]-Thiourea is known for its ability to interact with biological systems and is often used in pharmacological and medicinal chemistry research. Its unique structure and properties make it a valuable tool for studying the interaction between small molecules and biological targets. Additionally, its potential applications in various fields make it an intriguing subject of study for researchers and scientists.
Check Digit Verification of cas no
The CAS Registry Mumber 1248348-67-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,4,8,3,4 and 8 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1248348-67:
(9*1)+(8*2)+(7*4)+(6*8)+(5*3)+(4*4)+(3*8)+(2*6)+(1*7)=175
175 % 10 = 5
So 1248348-67-5 is a valid CAS Registry Number.
1248348-67-5Relevant articles and documents
Metal-free asymmetric 1,3-dipolar cycloaddition of N-arylmaleimides to azomethine ylides catalyzed by chiral tertiary amine thiourea
Bai, Jian-Fei,Wang, Liang-Liang,Peng, Lin,Guo, Yun-Long,Ming, Jun-Nan,Wang, Fei-Ying,Xu, Xiao-Ying,Wang, Li-Xin
experimental part, p. 4472 - 4478 (2011/10/01)
The first metal-free asymmetric 1,3-dipolar cycloaddition of N-arylmaleimides to azomethine ylides catalyzed by chiral tertiary amine thiourea to form multiply substituted pyrrolidines in excellent yields (up to 89%) and enantioselectivities (up to 96% ee) is presented. This procedure allows a rapid diversity-oriented synthesis of chiral pyrrolidine derivatives with high optical purity. A series of bifunctional thiourea catalysts were applied for the first time to the highly asymmetric 1,3-dipolar cycloaddition of N-arylmaleimides to azomethine ylides togive the products in excellent yields (up to 89%) and enantioselectivities (up to 96% ee).
