1248348-67-5 Usage
Uses
Used in Research and Experimental Studies:
N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(1S,2S)-2-(1-pyrrolidinyl)cyclohexyl]-Thiourea is used as a reagent in chemical reactions and synthesis processes, particularly in the field of medicinal chemistry. Its ability to interact with biological systems makes it a valuable tool for studying the interaction between small molecules and biological targets.
Used in Pharmacological Research:
In the pharmaceutical industry, N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(1S,2S)-2-(1-pyrrolidinyl)cyclohexyl]-Thiourea is used as a research compound to explore its potential applications in drug discovery and development. Its unique properties and interactions with biological systems make it a promising candidate for the development of new therapeutic agents.
Used in Medicinal Chemistry:
N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(1S,2S)-2-(1-pyrrolidinyl)cyclohexyl]-Thiourea is employed in medicinal chemistry research to investigate its potential as a lead compound for the development of new drugs. Its unique structure and properties allow researchers to study its interactions with biological targets and evaluate its potential therapeutic effects.
Used in Chemical Synthesis:
In the field of chemical synthesis, N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(1S,2S)-2-(1-pyrrolidinyl)cyclohexyl]-Thiourea is used as a reagent to facilitate the synthesis of various compounds. Its ability to participate in chemical reactions makes it a useful component in the development of new chemical entities.
Check Digit Verification of cas no
The CAS Registry Mumber 1248348-67-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,4,8,3,4 and 8 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1248348-67:
(9*1)+(8*2)+(7*4)+(6*8)+(5*3)+(4*4)+(3*8)+(2*6)+(1*7)=175
175 % 10 = 5
So 1248348-67-5 is a valid CAS Registry Number.
1248348-67-5Relevant academic research and scientific papers
Metal-free asymmetric 1,3-dipolar cycloaddition of N-arylmaleimides to azomethine ylides catalyzed by chiral tertiary amine thiourea
Bai, Jian-Fei,Wang, Liang-Liang,Peng, Lin,Guo, Yun-Long,Ming, Jun-Nan,Wang, Fei-Ying,Xu, Xiao-Ying,Wang, Li-Xin
experimental part, p. 4472 - 4478 (2011/10/01)
The first metal-free asymmetric 1,3-dipolar cycloaddition of N-arylmaleimides to azomethine ylides catalyzed by chiral tertiary amine thiourea to form multiply substituted pyrrolidines in excellent yields (up to 89%) and enantioselectivities (up to 96% ee) is presented. This procedure allows a rapid diversity-oriented synthesis of chiral pyrrolidine derivatives with high optical purity. A series of bifunctional thiourea catalysts were applied for the first time to the highly asymmetric 1,3-dipolar cycloaddition of N-arylmaleimides to azomethine ylides togive the products in excellent yields (up to 89%) and enantioselectivities (up to 96% ee).
