1248360-76-0Relevant academic research and scientific papers
Deracemization of axially chiral α,β-unsaturated aldehydes through an amino-catalyzed symmetry-making-symmetry-breaking cascade
Jiang, Hao,Halskov, Kim Soholm,Johansen, Tore Kiilerich,Jorgensen, Karl Anker
, p. 3842 - 3846 (2011)
Highly enantioenriched products have been prepared in good yields from racemic enal starting materials through a new deracemization strategy that employs an enantioconvergent amino-catalyzed symmetry-making-symmetry-breaking cascade. The reaction design features the tandem domination of product development and catalyst control in two reaction steps (see scheme).
