124837-37-2Relevant articles and documents
BROMODOMAIN INHIBITORS
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, (2017/11/10)
The present invention provides for compounds of formula (I) wherein R1, R2, R3, R4, R6, X1, and X2 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising compounds of formula (I).
Tert-butylphenyl compounds useful as anti-inflammatory agents
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, (2008/06/13)
The present invention involves compounds having the structure: STR1 wherein: (a) --A1 is selected from the group consisting of --OH, --H, and --O2 CR; (b) --A2 is selected from the group consisting of unsubstituted or substituted, saturated or unsaturated, straight, branched and cyclic alkyl having from 1 to about 10 carbon atoms; (c)--A3 is selected from --C(CH3)3, --Si(CH3)3, and --CF3 ; and (d) --Y is selected from certain low molecular weight alkyl chains which terminate in specific unsaturated functional groups: STR2 and aldehydes in the form of their acetals; pharmaceutical compositions comprising such compounds; and methods for treating inflammation by administering such compounds.